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Deamidation of Protonated Asparagine–Valine Investigated by a Combined Spectroscopic, Guided Ion Beam, and Theoretical Study

[Image: see text] Peptide deamidation of asparaginyl residues is a spontaneous post-translational modification that is believed to play a role in aging and several diseases. It is also a well-known small-molecule loss channel in the MS/MS spectra of protonated peptides. Here we investigate the deami...

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Detalles Bibliográficos
Autores principales: Kempkes, L. J. M., Boles, G. C., Martens, J., Berden, G., Armentrout, P. B., Oomens, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846081/
https://www.ncbi.nlm.nih.gov/pubmed/29436829
http://dx.doi.org/10.1021/acs.jpca.7b12348