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The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps

BACKGROUND: Chronic rhinosinusitis (CRS), commonly divided into CRS with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP) is an inflammatory disease which mechanism remain unclear. Leucine-rich repeat kinase 2 (LRRK2) has been proved to be a negative regulator of inflammation response while i...

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Detalles Bibliográficos
Autores principales: Ma, Yue, Zheng, Chunquan, Shi, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846253/
https://www.ncbi.nlm.nih.gov/pubmed/29545945
http://dx.doi.org/10.1186/s13601-018-0194-y