Histological transformation of adenocarcinoma to small cell carcinoma lung as a rare mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors: Report of a case with review of literature

A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment. Though drug resistance is inevitable, histological transformation to small cell lung...

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Detalles Bibliográficos
Autores principales: Hui, Monalisa, Uppin, Shantveer G, Stalin, Bala Joseph, Sadashivudu, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846268/
https://www.ncbi.nlm.nih.gov/pubmed/29487254
http://dx.doi.org/10.4103/lungindia.lungindia_347_17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846268/
https://www.ncbi.nlm.nih.gov/pubmed/29487254
http://dx.doi.org/10.4103/lungindia.lungindia_347_17

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