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Histological transformation of adenocarcinoma to small cell carcinoma lung as a rare mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors: Report of a case with review of literature

A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment. Though drug resistance is inevitable, histological transformation to small cell lung...

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Detalles Bibliográficos
Autores principales:	Hui, Monalisa, Uppin, Shantveer G, Stalin, Bala Joseph, Sadashivudu, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846268/ https://www.ncbi.nlm.nih.gov/pubmed/29487254 http://dx.doi.org/10.4103/lungindia.lungindia_347_17

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