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Local S100A8 Levels Correlate With Recurrence of Experimental Autoimmune Uveitis and Promote Pathogenic T Cell Activity

PURPOSE: To investigate the role of damage-associated molecular patterns (DAMPs) in recurrent experimental autoimmune uveitis (EAU). METHODS: Recurrent EAU was induced in Lewis rats by interphotoreceptor retinoid-binding protein (IRBP) R16-peptide specific T cells (tEAU). Aqueous humor and serum sam...

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Detalles Bibliográficos
Autores principales: Yun, Juan, Xiao, Tong, Zhou, Lei, Beuerman, Roger W., Li, Juanjuan, Zhao, Yuan, Hadayer, Amir, Zhang, Xiaomin, Sun, Deming, Kaplan, Henry J., Shao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846334/
https://www.ncbi.nlm.nih.gov/pubmed/29625456
http://dx.doi.org/10.1167/iovs.17-23127