Blood-Brain Barrier Damage as the Starting Point of Leukoaraiosis Caused by Cerebral Chronic Hypoperfusion and Its Involved Mechanisms: Effect of Agrin and Aquaporin-4

White matter lesion (WML) is popular in the patients aged over 65. Brain edema and blood-brain barrier (BBB) dysfunction due to cerebral chronic hypoperfusion (CCH) contributed to WML. Preserving astrocyte polarity is vital for BBB integrity. In our experiment, CCH model is established by bilateral...

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Detalles Bibliográficos
Autores principales: Huang, Jing, Li, Junwen, Feng, Chao, Huang, Xi, Wong, Liping, Liu, Xueyuan, Nie, Zhiyu, Xi, Gangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846350/
https://www.ncbi.nlm.nih.gov/pubmed/29682525
http://dx.doi.org/10.1155/2018/2321797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846350/
https://www.ncbi.nlm.nih.gov/pubmed/29682525
http://dx.doi.org/10.1155/2018/2321797

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