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Defective Autophagy in Atherosclerosis: To Die or to Senesce?

Autophagy is a subcellular process that plays an important role in the degradation of proteins and damaged organelles such as mitochondria (a process termed “mitophagy”) via lysosomes. It is crucial for regulating protein and mitochondrial quality control and maintaining cellular homeostasis, wherea...

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Detalles Bibliográficos
Autores principales: Grootaert, Mandy O. J., Roth, Lynn, Schrijvers, Dorien M., De Meyer, Guido R. Y., Martinet, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846382/
https://www.ncbi.nlm.nih.gov/pubmed/29682164
http://dx.doi.org/10.1155/2018/7687083