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Encapsulated Cell Technology-Based Delivery of a Complement Inhibitor Reduces Choroidal Neovascularization in a Mouse Model

PURPOSE: Age-related macular degeneration (AMD) is a slowly progressing disease, and risk appears to be tied to an overactive complement system. We have previously demonstrated that mouse choroidal neovascularization (CNV) and smoke-induced ocular pathology can be reduced with an alternative pathway...

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Detalles Bibliográficos
Autores principales: Annamalai, Balasubramaniam, Parsons, Nathaniel, Belhaj, Marwa, Brandon, Carlene, Potts, Jay, Rohrer, Bärbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846441/
https://www.ncbi.nlm.nih.gov/pubmed/29576927
http://dx.doi.org/10.1167/tvst.7.2.3