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Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates

PURPOSE: To characterize the intraocular immune response following transplantation of iPS-derived allogeneic RPE cells into the subretinal space of non–immune-suppressed rhesus macaques. METHODS: GFP-labeled allogeneic iPS-derived RPE cells were transplanted into the subretinal space of one eye (n =...

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Detalles Bibliográficos
Autores principales: McGill, Trevor J., Stoddard, Jonathan, Renner, Lauren M., Messaoudi, Ilhem, Bharti, Kapil, Mitalipov, Shoukhrat, Lauer, Andreas, Wilson, David J., Neuringer, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846443/
https://www.ncbi.nlm.nih.gov/pubmed/29625461
http://dx.doi.org/10.1167/iovs.17-22467