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Hypoxia induces pulmonary arterial fibroblast proliferation, migration, differentiation and vascular remodeling via the PI3K/Akt/p70S6K signaling pathway

The present study was designed to examine whether hypoxia induces the proliferation, migration and differentiation of pulmonary arterial fibroblasts (PAFs) via the PI3K/Akt/p70S6K signaling pathway. PAFs were subjected to normoxia (21% O(2)) or hypoxia (1% O(2)). The proliferation, migration, differ...

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Detalles Bibliográficos
Autores principales: Chai, Xiaoyu, Sun, Dan, Han, Qian, Yi, Liang, Wu, Yanping, Liu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846667/
https://www.ncbi.nlm.nih.gov/pubmed/29436587
http://dx.doi.org/10.3892/ijmm.2018.3462