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Sitagliptin ameliorates diabetic nephropathy by blocking TGF-β1/Smad signaling pathway

Diabetic nephropathy (DN) is the leading cause of end-stage failure of the kidney, but the efficacy of current strategies available for the prevention of DN remains unsatisfactory. The purpose of this study was to assess whether sitagliptin (SIT) has therapeutic potential for prevention of DN and to...

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Detalles Bibliográficos
Autores principales: Wang, Dongdong, Zhang, Guanying, Chen, Xiao, Wei, Tong, Liu, Chenxu, Chen, Chun, Gong, Yinhan, Wei, Qunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846674/
https://www.ncbi.nlm.nih.gov/pubmed/29484381
http://dx.doi.org/10.3892/ijmm.2018.3504