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Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci

Late-stage age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly with a complex etiology. The most important non-modifiable risk factors for onset and progression of late AMD are age and genetic risk factors, however, little is known about the interplay betw...

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Detalles Bibliográficos
Autores principales: Winkler, Thomas W., Brandl, Caroline, Grassmann, Felix, Gorski, Mathias, Stark, Klaus, Loss, Julika, Weber, Bernhard H. F., Heid, Iris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846797/
https://www.ncbi.nlm.nih.gov/pubmed/29529059
http://dx.doi.org/10.1371/journal.pone.0194321