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A single mitochondrial DNA deletion accurately detects significant prostate cancer in men in the PSA ‘grey zone’

PURPOSE: To determine the clinical performance of a blood-based test for clinically significant (CS) prostate cancer (PCa) (grade group ≥ 2) intended for use in men with prostate serum antigen levels in the ‘grey zone’ (PSA < 10 ng/ml). The test quantifies a previously described 3.4 kb mitochondr...

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Detalles Bibliográficos
Autores principales: Creed, Jennifer, Klotz, Laurence, Harbottle, Andrew, Maggrah, Andrea, Reguly, Brian, George, Anne, Gnanapragasm, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846823/
https://www.ncbi.nlm.nih.gov/pubmed/29248950
http://dx.doi.org/10.1007/s00345-017-2152-z