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Cardiomyocyte ionic currents in intact young and aged murine Pgc-1β(−/−) atrial preparations
INTRODUCTION: Recent studies reported that energetically deficient murine Pgc-1β(−/−) hearts replicate age-dependent atrial arrhythmic phenotypes associated with their corresponding clinical conditions, implicating action potential (AP) conduction slowing consequent upon reduced AP upstroke rates. M...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ireland
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846848/ https://www.ncbi.nlm.nih.gov/pubmed/29197478 http://dx.doi.org/10.1016/j.mad.2017.11.016 |