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Cardiomyocyte ionic currents in intact young and aged murine Pgc-1β(−/−) atrial preparations

INTRODUCTION: Recent studies reported that energetically deficient murine Pgc-1β(−/−) hearts replicate age-dependent atrial arrhythmic phenotypes associated with their corresponding clinical conditions, implicating action potential (AP) conduction slowing consequent upon reduced AP upstroke rates. M...

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Detalles Bibliográficos
Autores principales: Valli, Haseeb, Ahmad, Shiraz, Jiang, Anita Y., Smyth, Robert, Jeevaratnam, Kamalan, Matthews, Hugh R., Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846848/
https://www.ncbi.nlm.nih.gov/pubmed/29197478
http://dx.doi.org/10.1016/j.mad.2017.11.016