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Neuronal DNA Methyltransferases: Epigenetic Mediators between Synaptic Activity and Gene Expression?
DNMT3A and 3B are the main de novo DNA methyltransferases (DNMTs) in the brain that introduce new methylation marks to non-methylated DNA in postmitotic neurons. DNA methylation is a key epigenetic mark that is known to regulate important cellular processes in neuronal development and brain plastici...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846851/ https://www.ncbi.nlm.nih.gov/pubmed/28513272 http://dx.doi.org/10.1177/1073858417707457 |