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TRPV1 gain-of-function mutation impairs pain and itch sensations in mice
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel, which can detect various noxious stimuli that cause pain, inflammation, hyperalgesia, and itch. TRPV1 knock-out mice show deficiency in nociception, but the in vivo effects of persistent activation of TRPV1 are not c...
Autores principales: | Duo, Lina, Hu, Linghan, Tian, Naxi, Cheng, Gen, Wang, Huijun, Lin, Zhimiao, Wang, Yun, Yang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846932/ https://www.ncbi.nlm.nih.gov/pubmed/29424270 http://dx.doi.org/10.1177/1744806918762031 |
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