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Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation
How signaling dynamics encode information is a central question in biology. During vertebrate development, dynamic Notch signaling oscillations control segmentation of the presomitic mesoderm (PSM). In mouse embryos, this molecular clock comprises signaling oscillations of several pathways, i.e., No...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847172/ https://www.ncbi.nlm.nih.gov/pubmed/29474908 http://dx.doi.org/10.1016/j.cell.2018.01.026 |