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Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

How signaling dynamics encode information is a central question in biology. During vertebrate development, dynamic Notch signaling oscillations control segmentation of the presomitic mesoderm (PSM). In mouse embryos, this molecular clock comprises signaling oscillations of several pathways, i.e., No...

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Detalles Bibliográficos
Autores principales:	Sonnen, Katharina F., Lauschke, Volker M., Uraji, Julia, Falk, Henning J., Petersen, Yvonne, Funk, Maja C., Beaupeux, Mathias, François, Paul, Merten, Christoph A., Aulehla, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847172/ https://www.ncbi.nlm.nih.gov/pubmed/29474908 http://dx.doi.org/10.1016/j.cell.2018.01.026

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