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The impact of 27-hydroxycholesterol on endometrial cancer proliferation

Endometrial cancer (EC) is the most common gynaecological malignancy. Obesity is a major risk factor for EC and is associated with elevated cholesterol. 27-hydroxycholesterol (27HC) is a cholesterol metabolite that functions as an endogenous agonist for Liver X receptor (LXR) and a selective oestrog...

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Detalles Bibliográficos
Autores principales: Gibson, Douglas A, Collins, Frances, Cousins, Fiona L, Esnal Zufiaurre, Arantza, Saunders, Philippa T K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847183/
https://www.ncbi.nlm.nih.gov/pubmed/29371332
http://dx.doi.org/10.1530/ERC-17-0449