Pak1 Kinase Maintains Apical Membrane Identity in Epithelia

Epithelial cells are polarized along their apical-basal axis by the action of the small GTPase Cdc42, which is known to activate the aPKC kinase at the apical domain. However, loss of aPKC kinase activity was reported to have only mild effects on epithelial cell polarity. Here, we show that Cdc42 al...

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Detalles Bibliográficos
Autores principales: Aguilar-Aragon, Mario, Elbediwy, Ahmed, Foglizzo, Valentina, Fletcher, Georgina C., Li, Vivian S.W., Thompson, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847184/
https://www.ncbi.nlm.nih.gov/pubmed/29444419
http://dx.doi.org/10.1016/j.celrep.2018.01.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847184/
https://www.ncbi.nlm.nih.gov/pubmed/29444419
http://dx.doi.org/10.1016/j.celrep.2018.01.060

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