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Inferior Olive HCN1 Channels Coordinate Synaptic Integration and Complex Spike Timing

Cerebellar climbing-fiber-mediated complex spikes originate from neurons in the inferior olive (IO), are critical for motor coordination, and are central to theories of cerebellar learning. Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels expressed by IO neurons have been considere...

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Detalles Bibliográficos
Autores principales: Garden, Derek L.F., Oostland, Marlies, Jelitai, Marta, Rinaldi, Arianna, Duguid, Ian, Nolan, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847187/
https://www.ncbi.nlm.nih.gov/pubmed/29444426
http://dx.doi.org/10.1016/j.celrep.2018.01.069