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An examination of multiple classes of rare variants in extended families with bipolar disorder

Bipolar disorder (BD) is a complex psychiatric condition with high heritability, the genetic architecture of which likely comprises both common variants of small effect and rare variants of higher penetrance, the latter of which are largely unknown. Extended families with high density of illness pro...

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Detalles Bibliográficos
Autores principales: Toma, Claudio, Shaw, Alex D., Allcock, Richard J. N., Heath, Anna, Pierce, Kerrie D., Mitchell, Philip B., Schofield, Peter R., Fullerton, Janice M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847564/
https://www.ncbi.nlm.nih.gov/pubmed/29531218
http://dx.doi.org/10.1038/s41398-018-0113-y