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Cost-effective generation of precise label-free quantitative proteomes in high-throughput by microLC and data-independent acquisition

Quantitative proteomics is key for basic research, but needs improvements to satisfy an increasing demand for large sample series in diagnostics, academia and industry. A switch from nanoflowrate to microflowrate chromatography can improve throughput and reduce costs. However, concerns about undersa...

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Detalles Bibliográficos
Autores principales: Vowinckel, Jakob, Zelezniak, Aleksej, Bruderer, Roland, Mülleder, Michael, Reiter, Lukas, Ralser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847575/
https://www.ncbi.nlm.nih.gov/pubmed/29531254
http://dx.doi.org/10.1038/s41598-018-22610-4