General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept

The class I major histocompatibility complex (MHC) is capable of binding peptides derived from intracellular proteins and displaying them at the cell surface. The recognition of these peptide-MHC (pMHC) complexes by T-cells is the cornerstone of cellular immunity, enabling the elimination of infecte...

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Detalles Bibliográficos
Autores principales: Antunes, Dinler A., Devaurs, Didier, Moll, Mark, Lizée, Gregory, Kavraki, Lydia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847594/
https://www.ncbi.nlm.nih.gov/pubmed/29531253
http://dx.doi.org/10.1038/s41598-018-22173-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847594/
https://www.ncbi.nlm.nih.gov/pubmed/29531253
http://dx.doi.org/10.1038/s41598-018-22173-4

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