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General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept
The class I major histocompatibility complex (MHC) is capable of binding peptides derived from intracellular proteins and displaying them at the cell surface. The recognition of these peptide-MHC (pMHC) complexes by T-cells is the cornerstone of cellular immunity, enabling the elimination of infecte...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847594/ https://www.ncbi.nlm.nih.gov/pubmed/29531253 http://dx.doi.org/10.1038/s41598-018-22173-4 |