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Vesicular glutamate release from central axons contributes to myelin damage
The axon myelin sheath is prone to injury associated with N-methyl-d-aspartate (NMDA)-type glutamate receptor activation but the source of glutamate in this context is unknown. Myelin damage results in permanent action potential loss and severe functional deficit in the white matter of the CNS, for...
Autores principales: | Doyle, Sean, Hansen, Daniel Bloch, Vella, Jasmine, Bond, Peter, Harper, Glenn, Zammit, Christian, Valentino, Mario, Fern, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847599/ https://www.ncbi.nlm.nih.gov/pubmed/29531223 http://dx.doi.org/10.1038/s41467-018-03427-1 |
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