Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

The rising prevalence of chronic liver disease, coupled with a permanent shortage of organs for liver transplantation, has sparked enormous interest in alternative treatment strategies. Previous protocols to generate hepatocyte-like cells (HLCs) via pancreas-to-liver transdifferentiation have utilis...

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Detalles Bibliográficos
Autores principales: Gratte, Francis D., Pasic, Sara, Olynyk, John K., Yeoh, George C. T., Tosh, David, Coombe, Deirdre R., Tirnitz-Parker, Janina E. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847606/
https://www.ncbi.nlm.nih.gov/pubmed/29531353
http://dx.doi.org/10.1038/s41598-018-22596-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847606/
https://www.ncbi.nlm.nih.gov/pubmed/29531353
http://dx.doi.org/10.1038/s41598-018-22596-z

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