Cargando…

Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

The rising prevalence of chronic liver disease, coupled with a permanent shortage of organs for liver transplantation, has sparked enormous interest in alternative treatment strategies. Previous protocols to generate hepatocyte-like cells (HLCs) via pancreas-to-liver transdifferentiation have utilis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gratte, Francis D., Pasic, Sara, Olynyk, John K., Yeoh, George C. T., Tosh, David, Coombe, Deirdre R., Tirnitz-Parker, Janina E. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847606/ https://www.ncbi.nlm.nih.gov/pubmed/29531353 http://dx.doi.org/10.1038/s41598-018-22596-z

Ejemplares similares

Immune checkpoint inhibition: prospects for prevention and therapy of hepatocellular carcinoma
por: Elsegood, Caryn L, et al.
Publicado: (2017)

TWEAK and LTβ Signaling during Chronic Liver Disease
por: Dwyer, Benjamin J., et al.
Publicado: (2014)

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells
por: Genz, Berit, et al.
Publicado: (2019)

A Transcriptomic Signature of Mouse Liver Progenitor Cells
por: Passman, Adam M., et al.
Publicado: (2016)

Mesenchymal Stem Cells: Signaling Pathways in Transdifferentiation Into Retinal Progenitor Cells
por: Kadkhodaeian, Hamid Aboutaleb
Publicado: (2021)

Transdifferentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte progenitor cells
por: Ghasemi, Nazem
Publicado: (2018)

Impact of senescence on the transdifferentiation process of human hepatic progenitor-like cells
por: Bellanti, Francesco, et al.
Publicado: (2021)

β‐Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas
por: Kim, Hyo‐Sup, et al.
Publicado: (2016)

Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation
por: Limaye, Pallavi B, et al.
Publicado: (2010)

An Efficient and Footprint-Free Protocol for the Transdifferentiation of Hepatocytes Into Insulin-Producing Cells With IVT mRNAs
por: Ma, Shinan, et al.
Publicado: (2020)

MicroRNA-22 Can Reduce Parathymosin Expression in Transdifferentiated Hepatocytes
por: Chen, Hung-Lin, et al.
Publicado: (2012)

The role of insulin in transdifferentiated hepatocyte proliferation and function in serum‐free medium
por: Gu, Ce, et al.
Publicado: (2019)

IL‐8 induces transdifferentiation of mature hepatocytes toward the cholangiocyte phenotype
por: Sasaki, Tokio, et al.
Publicado: (2019)

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation
por: Schaub, Johanna R., et al.
Publicado: (2018)

Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules
por: Chen, Zheng, et al.
Publicado: (2017)

Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells
por: Yau, Winifred WY, et al.
Publicado: (2011)

Early Endothelial Progenitor Cells (eEPCs) in systemic sclerosis (SSc) - dynamics of cellular regeneration and mesenchymal transdifferentiation
por: Patschan, S., et al.
Publicado: (2016)

Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential
por: Carlessi, Rodrigo, et al.
Publicado: (2023)

Debates in Pancreatic Beta Cell Biology: Proliferation Versus Progenitor Differentiation and Transdifferentiation in Restoring β Cell Mass
por: Spears, Erick, et al.
Publicado: (2021)

TWEAK/Fn14 Signalling Regulates the Tissue Microenvironment in Chronic Pancreatitis
por: Abu Bakar, N. Dianah B., et al.
Publicado: (2023)

Secretome Analysis of Inductive Signals for BM-MSC Transdifferentiation into Salivary Gland Progenitors
por: Mona, Mahmoud, et al.
Publicado: (2020)

Next generation in vitro liver model design: Combining a permeable polystyrene membrane with a transdifferentiated cell line
por: Luetchford, Kim A., et al.
Publicado: (2018)

Combination of cell signaling molecules can facilitate MYOD1-mediated myogenic transdifferentiation of pig fibroblasts
por: Jeong, Jinsol, et al.
Publicado: (2021)

Development of immortalized human hepatocyte-like hybrid cells by fusion of multi-lineage progenitor cells with primary hepatocytes
por: Collins, Daniel P., et al.
Publicado: (2020)

Immunofluorescent characterization of non-myelinating Schwann cells and their interactions with immune cells in mouse mesenteric lymph node
por: Shi, Zhongli, et al.
Publicado: (2017)

Progressive induction of hepatocyte progenitor cells in chronically injured liver
por: Tanimizu, Naoki, et al.
Publicado: (2017)

Is transdifferentiation in trouble?
por: Wells, William A.
Publicado: (2002)

Biliary Migration, Colonization, and Pathogenesis of O. viverrini Co-Infected with CagA+ Helicobacter pylori
por: Suyapoh, Watcharapol, et al.
Publicado: (2021)

Differentiation and transdifferentiation potentials of cancer stem cells
por: Huang, Zhengjie, et al.
Publicado: (2015)

Transdifferentiation of differentiated stem cells contributes to remyelination
por: Chelluboina, Bharath, et al.
Publicado: (2015)

Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease Model
por: Passman, Adam M., et al.
Publicado: (2021)

When morphogenetic proteins encounter special extracellular matrix and cell-cell connections at the interface of the renal stem/progenitor cell niche
por: Minuth, Will W., et al.
Publicado: (2015)

The differentiation of human multipotent adult progenitor cells into hepatocyte-like cells induced by coculture with human hepatocyte line L02
por: Mu, Ning, et al.
Publicado: (2015)

Transdifferentiation of Human Dental Pulp Stem Cells Into Oligoprogenitor Cells
por: Moayeri, Ardeshir, et al.
Publicado: (2017)

The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis
por: Wai Wong, Chee, et al.
Publicado: (2012)

YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy
por: Jin, Bo, et al.
Publicado: (2018)

mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance
por: Meroni, Marica, et al.
Publicado: (2019)

ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver
por: Xu, Jianliang, et al.
Publicado: (2022)

Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration
por: Lan, Tian, et al.
Publicado: (2023)

Transdifferentiation of pancreatic cells by loss of contact-mediated signaling
por: Back, Walter de, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_h4ett98ofmgo8c3e8csrp31jlk