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Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Vesicular stomatitis virus (VSV) is an oncolytic rhabdovirus and its glycoprotein G is widely used to pseudotype other viruses for gene therapy. Low-density lipoprotein receptor (LDL-R) serves as a major entry receptor for VSV. Here we report two crystal structures of VSV G in complex with two disti...

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Detalles Bibliográficos
Autores principales: Nikolic, Jovan, Belot, Laura, Raux, Hélène, Legrand, Pierre, Gaudin, Yves, A. Albertini, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847621/
https://www.ncbi.nlm.nih.gov/pubmed/29531262
http://dx.doi.org/10.1038/s41467-018-03432-4