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The 116G > A MSH6 and IVS1-1121C > T PMS2 Genes Polymorphisms Modulate the Risk of the Sporadic Colorectal Cancer Development in Polish Population

Colorectal cancer (CRC) is one of the most common cancers worldwide. DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects mismatches generated during DNA replication. MMR defects were found to be associated with hereditary non-polyposis colorectal cancer (HNPCC) and a subse...

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Detalles Bibliográficos
Autores principales: Zelga, Piotr, Przybyłowska-Sygut, Karolina, Zelga, Marta, Dziki, Adam, Majsterek, Ireneusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847625/
https://www.ncbi.nlm.nih.gov/pubmed/28451866
http://dx.doi.org/10.1007/s12253-017-0231-5