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Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast
The yeast Saccharomyces cerevisiae is widely used as a cell factory to produce recombinant proteins. However, S. cerevisiae naturally secretes only a few proteins, such as invertase and the mating alpha factor, and its secretory capacity is limited. It has been reported that engineering protein ante...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847638/ https://www.ncbi.nlm.nih.gov/pubmed/29532188 http://dx.doi.org/10.1186/s13568-018-0571-x |