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The mitochondrial ATP synthase is a shared drug target for aging and dementia

Aging is a major driving force underlying dementia, such as that caused by Alzheimer's disease (AD). While the idea of targeting aging as a therapeutic strategy is not new, it remains unclear how closely aging and age‐associated diseases are coupled at the molecular level. Here, we discover a n...

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Detalles Bibliográficos
Autores principales: Goldberg, Joshua, Currais, Antonio, Prior, Marguerite, Fischer, Wolfgang, Chiruta, Chandramouli, Ratliff, Eric, Daugherty, Daniel, Dargusch, Richard, Finley, Kim, Esparza‐Moltó, Pau B., Cuezva, José M., Maher, Pamela, Petrascheck, Michael, Schubert, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847861/
https://www.ncbi.nlm.nih.gov/pubmed/29316249
http://dx.doi.org/10.1111/acel.12715