ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis

PINK1 (PTEN‐induced putative kinase 1) is a key regulator of mitochondrial homeostasis that is relatively depleted in aging lungs and in lung epithelial cells from patients with idiopathic pulmonary fibrosis (IPF), a disease linked with aging. Impaired PINK1 expression and accumulation of damaged mi...

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Detalles Bibliográficos
Autores principales: Bueno, Marta, Brands, Judith, Voltz, Lauren, Fiedler, Kaitlin, Mays, Brenton, St. Croix, Claudette, Sembrat, John, Mallampalli, Rama K., Rojas, Mauricio, Mora, Ana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866/
https://www.ncbi.nlm.nih.gov/pubmed/29363258
http://dx.doi.org/10.1111/acel.12720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866/
https://www.ncbi.nlm.nih.gov/pubmed/29363258
http://dx.doi.org/10.1111/acel.12720

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