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ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis
PINK1 (PTEN‐induced putative kinase 1) is a key regulator of mitochondrial homeostasis that is relatively depleted in aging lungs and in lung epithelial cells from patients with idiopathic pulmonary fibrosis (IPF), a disease linked with aging. Impaired PINK1 expression and accumulation of damaged mi...
Autores principales: | Bueno, Marta, Brands, Judith, Voltz, Lauren, Fiedler, Kaitlin, Mays, Brenton, St. Croix, Claudette, Sembrat, John, Mallampalli, Rama K., Rojas, Mauricio, Mora, Ana L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866/ https://www.ncbi.nlm.nih.gov/pubmed/29363258 http://dx.doi.org/10.1111/acel.12720 |
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