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Long‐lasting pathological consequences of overexpression‐induced α‐synuclein spreading in the rat brain

Increased expression of α‐synuclein can initiate its long‐distance brain transfer, representing a potential mechanism for pathology spreading in age‐related synucleinopathies, such as Parkinson's disease. In this study, the effects of overexpression‐induced α‐synuclein transfer were assessed ov...

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Detalles Bibliográficos
Autores principales: Rusconi, Raffaella, Ulusoy, Ayse, Aboutalebi, Helia, Di Monte, Donato A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847868/
https://www.ncbi.nlm.nih.gov/pubmed/29383832
http://dx.doi.org/10.1111/acel.12727