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Smurf2 regulates stability and the autophagic–lysosomal turnover of lamin A and its disease‐associated form progerin

A‐lamins, encoded by the LMNA gene, are major structural components of the nuclear lamina coordinating essential cellular processes. Mutations in the LMNA gene and/or alterations in its expression levels have been linked to a distinct subset of human disorders, collectively known as laminopathies, a...

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Detalles Bibliográficos
Autores principales: Borroni, Aurora Paola, Emanuelli, Andrea, Shah, Pooja Anil, Ilić, Nataša, Apel‐Sarid, Liat, Paolini, Biagio, Manikoth Ayyathan, Dhanoop, Koganti, Praveen, Levy‐Cohen, Gal, Blank, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847874/
https://www.ncbi.nlm.nih.gov/pubmed/29405587
http://dx.doi.org/10.1111/acel.12732