Overexpression of PGC‐1α in aging muscle enhances a subset of young‐like molecular patterns

PGC‐1α is a transcriptional co‐activator known as the master regulator of mitochondrial biogenesis. Its control of metabolism has been suggested to exert critical influence in the aging process. We have aged mice overexpressing PGC‐1α in skeletal muscle to determine whether the transcriptional chang...

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Detalles Bibliográficos
Autores principales: Garcia, Sofia, Nissanka, Nadee, Mareco, Edson A., Rossi, Susana, Peralta, Susana, Diaz, Francisca, Rotundo, Richard L., Carvalho, Robson F., Moraes, Carlos T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847875/
https://www.ncbi.nlm.nih.gov/pubmed/29427317
http://dx.doi.org/10.1111/acel.12707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847875/
https://www.ncbi.nlm.nih.gov/pubmed/29427317
http://dx.doi.org/10.1111/acel.12707

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