Cargando…

Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults

Administration of metformin increases healthspan and lifespan in model systems, and evidence from clinical trials and observational studies suggests that metformin delays a variety of age‐related morbidities. Although metformin has been shown to modulate multiple biological pathways at the cellular...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulkarni, Ameya S, Brutsaert, Erika F, Anghel, Valentin, Zhang, Kehao, Bloomgarden, Noah, Pollak, Michael, Mar, Jessica C, Hawkins, Meredith, Crandall, Jill P, Barzilai, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847877/
https://www.ncbi.nlm.nih.gov/pubmed/29383869
http://dx.doi.org/10.1111/acel.12723