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Transcriptomics of aged Drosophila motor neurons reveals a matrix metalloproteinase that impairs motor function

The neuromuscular junction (NMJ) is responsible for transforming nervous system signals into motor behavior and locomotion. In the fruit fly Drosophila melanogaster, an age‐dependent decline in motor function occurs, analogous to the decline experienced in mice, humans, and other mammals. The molecu...

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Detalles Bibliográficos
Autores principales: Azpurua, Jorge, Mahoney, Rebekah E., Eaton, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847883/
https://www.ncbi.nlm.nih.gov/pubmed/29411505
http://dx.doi.org/10.1111/acel.12729