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JC Virus-DNA Detection Is Associated with CD8 Effector Accumulation in Peripheral Blood of Patients with Multiple Sclerosis under Natalizumab Treatment, Independently from JC Virus Serostatus

Although natalizumab (anti-α4 integrin) represents an effective therapy for relapsing remitting multiple sclerosis (RRMS), it is associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML), caused by the polyomavirus JC (JCV). The aim of this study was to explore...

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Detalles Bibliográficos
Autores principales: Zingaropoli, Maria A., Iannetta, Marco, Pontecorvo, Simona, Anzivino, Elena, Prezioso, Carla, Rodio, Donatella Maria, Morreale, Manuela, D'Abramo, Alessandra, Oliva, Alessandra, Lichtner, Miriam, Cortese, Antonio, Frontoni, Marco, Pietropaolo, Valeria, Francia, Ada, Mastroianni, Claudio M., Vullo, Vincenzo, Ciardi, Maria R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848061/
https://www.ncbi.nlm.nih.gov/pubmed/29682547
http://dx.doi.org/10.1155/2018/5297980