A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy

Mycobacterium leprae causes leprosy and is unique among mycobacterial diseases in producing peripheral neuropathy. This debilitating morbidity is attributed to axon demyelination resulting from direct interaction of the M. leprae-specific phenolic glycolipid 1 (PGL-1) with myelinating glia and their...

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Detalles Bibliográficos
Autores principales: Madigan, Cressida A., Cambier, C.J., Kelly-Scumpia, Kindra M., Scumpia, Philip O., Cheng, Tan-Yun, Zailaa, Joseph, Bloom, Barry R., Moody, D. Branch, Smale, Stephen T., Sagasti, Alvaro, Modlin, Robert L., Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848073/
https://www.ncbi.nlm.nih.gov/pubmed/28841420
http://dx.doi.org/10.1016/j.cell.2017.07.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848073/
https://www.ncbi.nlm.nih.gov/pubmed/28841420
http://dx.doi.org/10.1016/j.cell.2017.07.030

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