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A Pyridazine-Based Fluorescent Probe Targeting Aβ Plaques in Alzheimer's Disease

Accumulation of β-amyloid (Aβ) plaques comprising Aβ40 and Aβ42 in the brain is the most significant factor in the pathogenesis of Alzheimer's disease (AD). Thus, the detection of Aβ plaques has increasingly attracted interest in the context of AD diagnosis. In the present study, a fluorescent...

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Detalles Bibliográficos
Autores principales: Park, Yong Dae, Kim, Jeum-Jong, Lee, Sungbeom, Park, Chul-Hong, Bai, Hyoung-Woo, Lee, Seung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848141/
https://www.ncbi.nlm.nih.gov/pubmed/29682395
http://dx.doi.org/10.1155/2018/1651989