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The Level of TWIST1 expression determines the response of colon cancer cells to mitogen-activated protein kinases inhibitors

BACKGROUND/AIM: Currently, it has been proposed that combination of 5-fluorouracil (5FU) with inhibitors of the mitogen-activated protein kinases (MAPKs) signaling pathway might enhance the efficacy of 5FU-based chemotherapy in colon cancer. Our study aimed to investigate an impact of TWIST1 silenci...

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Detalles Bibliográficos
Autores principales: Przybyla, Tomasz, Wesserling, Martyna, Sakowicz-Burkiewicz, Monika, Maciejewska, Izabela, Pawelczyk, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848323/
https://www.ncbi.nlm.nih.gov/pubmed/29451183
http://dx.doi.org/10.4103/sjg.SJG_270_17