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Inferring RNA sequence preferences for poorly studied RNA-binding proteins based on co-evolution

BACKGROUND: Characterizing the binding preference of RNA-binding proteins (RBP) is essential for us to understand the interaction between an RBP and its RNA targets, and to decipher the mechanism of post-transcriptional regulation. Experimental methods have been used to generate protein-RNA binding...

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Detalles Bibliográficos
Autores principales: Yang, Shu, Wang, Junwen, Ng, Raymond T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848454/
https://www.ncbi.nlm.nih.gov/pubmed/29529991
http://dx.doi.org/10.1186/s12859-018-2091-8