Physical basis of the ‘magnification rule’ for standardized Immunohistochemical scoring of HER2 in breast and gastric cancer

BACKGROUND: Detection of HER2/neu receptor overexpression and/or amplification is a prerequisite for efficient anti-HER2 treatment of breast and gastric carcinomas. Immunohistochemistry (IHC) of the HER2 protein is the most common screening test, thus precise and reproducible IHC-scoring is of utmos...

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Detalles Bibliográficos
Autores principales: Scheel, Andreas H., Penault-Llorca, Frédérique, Hanna, Wedad, Baretton, Gustavo, Middel, Peter, Burchhardt, Judith, Hofmann, Manfred, Jasani, Bharat, Rüschoff, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848460/
https://www.ncbi.nlm.nih.gov/pubmed/29530054
http://dx.doi.org/10.1186/s13000-018-0696-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848460/
https://www.ncbi.nlm.nih.gov/pubmed/29530054
http://dx.doi.org/10.1186/s13000-018-0696-x

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