Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages

BACKGROUND: Mer tyrosine kinase (MerTK) activity necessary for amyloid-stimulated phagocytosis strongly implicates that MerTK dysregulation might contribute to chronic inflammation implicated in Alzheimer’s disease (AD) pathology. However, the precise mechanism involved in the regulation of MerTK ex...

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Detalles Bibliográficos
Autores principales: Jhang, Kyoung A., Park, Jin-Sun, Kim, Hee-Sun, Chong, Young Hae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848511/
https://www.ncbi.nlm.nih.gov/pubmed/29530050
http://dx.doi.org/10.1186/s12974-018-1112-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848511/
https://www.ncbi.nlm.nih.gov/pubmed/29530050
http://dx.doi.org/10.1186/s12974-018-1112-x

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