Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures

Thrombopoietin (TPO) is a critical cytokine regulating hematopoietic stem cell maintenance and differentiation into the megakaryocytic lineage. However, the transcriptional and chromatin dynamics elicited by TPO signaling are poorly understood. Here, we study the immediate early transcriptional and...

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Detalles Bibliográficos
Autores principales: Comoglio, Federico, Park, Hyun Jung, Schoenfelder, Stefan, Barozzi, Iros, Bode, Daniel, Fraser, Peter, Green, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848609/
https://www.ncbi.nlm.nih.gov/pubmed/29429976
http://dx.doi.org/10.1101/gr.227272.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848609/
https://www.ncbi.nlm.nih.gov/pubmed/29429976
http://dx.doi.org/10.1101/gr.227272.117

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