ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters

High expression of the transcription factor ZFX is correlated with proliferation, tumorigenesis, and patient survival in multiple types of human cancers. However, the mechanism by which ZFX influences transcriptional regulation has not been determined. We performed ChIP-seq in four cancer cell lines...

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Detalles Bibliográficos
Autores principales: Rhie, Suhn Kyong, Yao, Lijun, Luo, Zhifei, Witt, Heather, Schreiner, Shannon, Guo, Yu, Perez, Andrew A., Farnham, Peggy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848610/
https://www.ncbi.nlm.nih.gov/pubmed/29429977
http://dx.doi.org/10.1101/gr.228809.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848610/
https://www.ncbi.nlm.nih.gov/pubmed/29429977
http://dx.doi.org/10.1101/gr.228809.117

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