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Reconstructing differentiation networks and their regulation from time series single-cell expression data

Generating detailed and accurate organogenesis models using single-cell RNA-seq data remains a major challenge. Current methods have relied primarily on the assumption that descendant cells are similar to their parents in terms of gene expression levels. These assumptions do not always hold for in v...

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Detalles Bibliográficos
Autores principales: Ding, Jun, Aronow, Bruce J., Kaminski, Naftali, Kitzmiller, Joseph, Whitsett, Jeffrey A., Bar-Joseph, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848617/
https://www.ncbi.nlm.nih.gov/pubmed/29317474
http://dx.doi.org/10.1101/gr.225979.117