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A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis
DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins. Here, we identify xNuRD, an MTA2-containing assemblage of the nucleosome remodeling and his...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848848/ https://www.ncbi.nlm.nih.gov/pubmed/29490265 http://dx.doi.org/10.1016/j.celrep.2018.02.015 |